| Dedication |
| Preface |
| CELLULAR DNA REPLICATION |
| 1 | Duplication of DNA in Eukaryotic Cells Thomas J. Kelly and Bruce Stillman |
| 2 | Eukaryotic DNA Replication Origins Mirit I. Aladjem, Arturo Falaschi, and David Kowalski |
| 3 | Assembly of Pre-replication Complexes Umasundari Sivaprasad, Anindya Dutta, and Stephen P. Bell |
| 4 | Activation of Pre-replication Complexes Johannes C. Walter and Hiroyuki Araki |
| 5 | Eukaryotic DNA Replication Forks Peter M.J. Burgers and Yeon-Soo Seo |
| 6 | Chromatin Assembly Paul D. Kaufman and Geneviève Almouzni |
| 7 | Inheritance of Genomic Methylation Patterns Robert A. Rollins, Marc Damelin, and Timothy H. Bestor |
| 8 | Termination of DNA Replication Deepak Bastia and Bidyut K. Mohanty |
| 9 | DNA Replication and Nuclear Architecture David M. Gilbert and Susan M. Gasser |
| 10 | Temporal Order of DNA Replication Anne D. Donaldson and Carl L. Schildkraut |
| 11 | DNA Replication during Animal Development and Its Relevance to Gene Expression Damien Grégoire and Marcel Méchali |
| 12 | Developmental Gene Amplification Brian R. Calvi |
| 13 | Plant Cells and Viruses Crisanto Gutierrez |
| 14 | Archaeal, Bacterial, and Eukaryal DNA Replication Machines Stephen D. Bell |
| REGULATION OF DNA REPLICATION AND CELL PROLIFERATION |
| 15 | Regulating Initiation Events in Yeasts Etienne Schwob and Karim Labib |
| 16 | Regulating Initiation Events in Metazoa Melvin L. DePamphilis and J. Julian Blow |
| 17 | Responses to Aberrant DNA Replication and DNA Damage in Yeasts Marco Foiani, Sanjay Kumar, and Joel A. Huberman |
| 18 | Responses to Aberrant DNA Replication and DNA Damage in Metazoa Jean Gautier and Jiri Bartek |
| CELLULAR DNA REPLICATION AND HUMAN DISEASE |
| 19 | DNA Damage and Human Disease Errol C. Friedberg |
| 20 | DNA Polymerases and the Fidelity of DNA Replication Polina V. Shcherbakova and Thomas A. Kunkel |
| 21 | The Role of RF-C and PCNA Proteins in Maintaining Genomic Stability Toshiki Tsurimoto |
| 22 | DNA Helicases and Human Disease Ashwini S. Kamath-Loeb, Michael Fry, and Lawrence A. Loeb |
| 23 | DNA Replication, Repeat Instability, and Human Disease John D. Cleary, Albert R. La Spada, and Christopher E. Pearson |
| 24 | DNA Replication and Cancer William C. Burhans, Antony M. Carr, and Geoffrey M. Wahl |
| 25 | Cancer Diagnosis and DNA Replication Nicholas Coleman, Anthony D. Mills, and Ronald A. Laskey |
| 26 | Pharmacological Agents That Target DNA Replication Yves Pommier and Robert B. Diasio |
| 27 | Mitochondrial DNA Replication and Human Disease David A. Clayton and Nils-Göran Larsson |
| 28 | Telomere DNA Replication, Telomerase, and Human Disease David C.F. Sealey, Virginia A. Zakian, and Lea Harrington |
| VIRAL DNA REPLICATION AND HUMAN DISEASE |
| 29 | Parvovirus Susan F. Cotmore and Peter Tattersall |
| 30 | Papillomavirus Louise T. Chow and Thomas R. Broker |
| 31 | Polyomavirus Ellen Fanning and James M. Pipas |
| 32 | Adenovirus Peter C. van der Vliet and Rob C. Hoeben |
| 33 | Herpes Simplex Virus Sandra K. Weller and Donald M. Coen |
| 34 | Epstein-Barr Virus Wolfgang Hammerschmidt and Bill Sugden |
| 35 | Poxvirus Bernard Moss and Frank De Silva |
| 36 | Hepadnavirus Christoph Seeger and William S. Mason |
| APPENDIX 1 |
| A. | Molecular Interaction Maps of DNA Replication Mirit I. Aladjem and Kurt W. Kohn |
| B. | The Evolutionary History of Proteins Involved in Pre-replication Complex Assembly Lakshminarayan M. Iyer and L. Aravind |
| APPENDIX 2 |
| Table I. | Size and Complexity of Eukaryotic Genomes |
| Table II. | Names and Abbreviations for Organisms, Genes, and Protein Complexes |
| Table III. | Nomenclature for Proteins and Protein Complexes in Different Organisms |
| Table IVA. | Phyletic Distribution of Proteins Involved in Pre-replication Complex Assembly |
| Table IVB. | Alternative Names for Orthologs |
| Table V. | Cellular Concentrations of Replication Origins and Pre-replication Complex Proteins |
| Table VI. | Human Diseases Associated with Defects in DNA Replication or Repair |
| Table VII. | Therapeutic Drugs That Target DNA Replication |
| Index |
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